SPLICE Theatrical Trailer

Released by WB, MSN has the trailer for the upcoming sci-fi suspense/thriller SPLICE, directed by Vincenzo Natali starring Sarah Polley and Adrien Brody, exec produced by the great Guillermo Del Toro. You can watch it using the media player below. Dark Castle bought it at Sundance and it will hit theaters on June 4th, 2010. If you really want to see what they’ve created, the trailer doesn’t give a good look at the thing in its developed stages, but it does reveal much of the early parts of the plot…

Clive and Elsa are superstars of the genetic engineering world. They specialize in splicing together DNA from different animals to create fantastical new hybrids. The charismatic couple wants to use human DNA in a new hybrid – something that could yield astronomical medical benefits. The pharmaceutical company that funds their research, however, is more interested in exploiting their earlier triumphs for easier, short-term profit. Clive and Elsa secretly conduct their own experiment. The result is Dren: an amazing creature who exhibits an array of unexpected developments, both physical and intellectual. Dren exceeds their wildest dreams… and, ultimately, their most terrifying nightmare.

SPLICE opens June 4th, 2010